Department of Pathology & Laboratory Medicine
Gabrielle deCourten-Myers, M.D.University of Zurich, Switzerland, M.D., 1974
Dr. deCourten-Myers directs the Division of Neuropathology and serves as a consultant for brain, muscle, and nerve biopsies and for nervous system abnormalities or postmortem exams.
Dr. deCourten-Myers’ multidisciplinary research program of experimental neuropathology investigates pathophysiologic mechanisms of brain injury from strokes (arterial occlusions and parenchymal hemorrhages) and from lack of oxygen, glucose and blood perfusion with the aim to develop more effective modalities of prevention and treatment. Collaborative stroke studies have demonstrated a major influence of blood glucose level on infarct size and our studies of brain hemorrhages have led to new concepts and treatments for this most deadly form of stroke. Another aspect of brain research involves morphometric studies of the normal, human cerebral cortex development from the fetus to the adult. These studies have provided evidence for and the timing of neuronal apoptotic cell death in man and have demonstrated fundamental gender differences in the structure of the cerebral cortex.
Recent Publications:
- Rabinowicz T, Petetot J McD-C, Gartside P, Sheyn D, Sheyn T, deCourten-Myers GM: Structure of the cerebral cortex in men and women. Accepted for publication by J Neuropathol. Exp. Neurol 9/01.
- Irazuzta JE, deCourten-Myers, GM, Zemlan, FP, Bekkedal MYV, Rossi J III: Serum cleaved tau protein and neurobehavioral battery of tests as markers of brain injury in experimental bacterial meningitis. Accepted for publication by Brain Research, 6/01.
- Stanek J, deCourten-Myers, GM, Spaulding A, Strub W, Hopkin RJ: A case of complex craiofacial anomalies, bilateral nasal probiscides, palatal pituitary, upper limbs reduction and amnion rupture sequence: disorganization phenotype? Pediatr. Develop. Pathol, 4: 192-202, 2001.
- deCourten-Myers GM, Xi G, Hwang J-H, Dunn RS, Mills AS, Holland SK, Wagner KR, and Myers, RE: Hypoglycemic brain injury: Potentiation from respiratory depression and injury aggravation from hyperglycemic treatment overshoots. J Cerebr Blood Flow Metabol (1):82-92, 2000.
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