One of our research goals is to gain a better understanding of the mechanisms and factors regulating intestinal lipid absorption and the assembly and secretion of chylomicrons and very low density lipoproteins by the small intestine.
The techniques we employ consist of conscious intestinal lymph fistula rats, lymph fistula mouse, intestinal epithelial cell culture, and also molecular biology.
We are currently studying how bile salts are involved in the absorption of lipids. In addition, we are also studying the factors regulating the synthesis and secretion of apolipoproteins by the small intestine.
The apolipoproteins we are studying are: apo AI, apo AIV, apo B, and apo CIII.